Authorities cordoned off an area around the crash scene near McClellan Drive and Poplar Boulevard.
Officials said the incident began when a man visited a friend's house not far from there.
Witnesses told investigators that two other men approached the man's red car. A short time later, shots were fired.
Deputies said the man sped away in the car, crashing it into a tree and suffering fatal injuries.
Investigators said they are still searching for the two men who confronted the man.